Conservative estimates suggest that ⩾25% of the world's population is at risk of zinc deficiency. Zinc deficiency was, for example, reported to affect the immune response and the endocrine system and to induce and modify brain disorders. Zinc deficiency is prevalent in many areas of the world and is a diagnostically challenging condition. Zinc deficiency is a major cause of childhood morbidity and mortality in developing countries (3, 4).Deficiency itself is common, although its prevalence varies in different countries, as judged from differences in plasma zinc between populations ().Zinc supplements reduce the incidence of diarrhea and probably mortality ().Thus, the 2008 Copenhagen consensus meeting … A recent trial in Ethiopia demonstrated a high risk of zinc deficiency among young children, particularly among those … Although it has been known for more than six decades that zinc is essential for the growth of micro-organisms, plants, and animals, until 1961 it was believed that zinc deficiency in humans could never occur. The global prevalence of zinc deficiency, measured as the share of the total population with intakes below physiological requirements, 1990-2005. Common signs and symptoms of a zinc deficiency include canker sores, deformed nails, hair loss, and rashes. Furthermore, in children, zinc deficiency along with iron deficiency is related to memory deficits. It is now clear that nutritional deficiency of zinc is widely prevalent and its morbidities are severe. For the study, researchers from Emory University examined… Zinc supplements must be used with caution in view of the dangers of zinc excess and zinc toxicity. zinc concentration is a useful indicator of population zinc status, as described below in more detail. Zinc is a trace element essential to the gastrointestinal, immune, integumentary, reproductive, and central nervous systems. Zinc is essential to good health and immunocompetence. Its deficiency is generally associated with a negative impact on overall health, increased susceptibility to disease, and infections [9-12]. The majority of countries found that zinc deficiency is a public health concern, and it is recommended that preventive zinc interventions should be considered in these settings. Besides hereditary zinc deficiency, zinc deficiency – at least in mild forms – is nowadays a very abundant health issue. Zinc is an essential trace element for humans and plays a critical role both as a structural component of proteins and as a cofactor in about 300 enzymes. Zinc deficiency (ZnD) is also prevalent in 25.6% of the population based on serum Zn level tests. This occurs because zinc deficiency can change the way the kidneys process sodium. Zinc intake is closely related to protein intake; as a result, zinc deficiency is an important component of nutritionally related morbidity worldwide . Zinc supplementation trials assessing the response of growth and immunity have assisted in identifying populations at risk of zinc deficiency and the factors that contribute. Bahmer and Bader have observed that zinc and biotin levels are reduced in patients with chronic alcohol use disorder and this may be associated with skin-related symptoms such as severe skin inflammation, the formation of rashes, crusts and scales, alopecia.. A case report published in 2000 … In a logistic model with relevant predictors, zinc deficiency was positively associated with gender and with serum albumin level. Most high-income countries, especially across Europe, North America, Oceania and Central Asia have incidences of zinc deficiency below 5-10 percent of the total population. There was a significant difference in zinc deficiency prevalence between the control group (14.4%) and the patient group (41.0%) (χ 2 = 44.81, df = 1, p<0.001). Data on zinc deficiency based on population surveys are still lacking from many developing countries (13, 14). The effects of zinc deficiency in humans is widely varied since zinc … ... By 2050 the world’s population will reach 9.1 billion. Because the largest source of dietary zinc in the study population was milk, this deficiency may be the result of these individuals’ avoidance of dairy. Individuals with IBS had significantly higher ratios of copper to zinc (1.70 vs 1.55, P =.048) and were more likely to have ratios >1.8 (OR, 1.79; 95% CI, 1.02-3.13), which suggests an underlying zinc deficiency. Zinc deficiency affects around 17% of the world’s population, mostly in developing countries. Serum zinc was used to determine the zinc status of the population because it is known as the best biomarker for zinc. Zinc deficiency impairs immune function and increases the susceptibility to infection, restricts physical growth and affects pregnancy outcome. Results. Zinc Deficiency: Descriptive Epidemiology and Morbidity among Preschool Children in Peri-urban Population in Delhi, India October 2009 Journal of Health Population and Nutrition 27(5):632-9 Indications for zinc supplementation. Congenital Zinc Deficiency. Zinc is one of the minerals that people all over the world tend to lack. Cutaneous manifestations typically occur in moderate to severe zinc deficiency and present as alopecia and dermatitis in the perioral, acral, and perineal regions. In Pakistan, the most recent national nutrition survey indicated that over 40% of women are zinc deficient. The large quantities of phytate” and fiber” in the diet of the rural population in Iran are thought to be major etiologic factors in the zinc deficiency of adolescents with nutritional dwarfism … National risk of zinc deficiency based on the prevalence of childhood stunting and the estimated prevalence of inadequate zinc intake (Wessells & Brown, 2012) Conservative estimates suggest that 25% of the world’s population is at risk of zinc deficiency ( 12 ). Young children and pregnant and lactating women are the most vulnerable population groups at risk of zinc deficiency. Could using a new type of flour in cooking help tackle this deficiency? 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